Over the past decades, airlines have started (and failed) in almost every region of the world. Not all of the problems are created by airline istelf. Airline business is susceptible to strong influences from many factors, government intervention (positive and negative) and, at times, illogical competitive behaviours. However, participating in several and studying a number of startups, our team has found many had common errors. The right strategy can create opportunities to build efficient airlines, in cargo as well as passenger segment, both full service, and low cost. But doing so also needs the right team, with right competencies, the right tools, the right aircraft and the right network to create ideal product.